A pioneering partnership between researchers from The Grainger College of Engineering at the University of Illinois Urbana-Champaign has produced a novel nanopore sensing platform for ...

Nanopore sensors are tiny devices used to detect and analyze individual molecules by measuring ionic changes as the molecules pass through nanometer-scale openings. These sensors are classified into ...

This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

A new study shows that long-read sequencing has the potential to improve the rate of diagnosis while reducing the time to diagnosis from years to days -- in a single test and at a much lower cost. One ...