In certain contexts, the Notch receptor may participate in “reverse signaling,” influencing neighboring cells directly.

All cells, whether big or small, short or long, rely on proteins to function properly. In most cells, transporting these proteins is relatively simple. Neurons in the brain, however, face a ...

Key market opportunities lie in developing IL-6 inhibitors for underexplored indications like atherosclerotic cardiovascular disease and thyroid eye disease. The IL-6 targeted therapy market gains ...

T cell activation—the process by which these key immune defenders recognize threats and mobilize against them—depends on exquisitely timed molecular signals. Now researchers have captured one of the ...

INDIGO Biosciences today announced the launch of its Transrepression Assay Services, expanding the company’s cell-based reporter assay capabilities for drug discovery teams studying pathway cross-talk ...

Researchers say findings may have relevance to understanding cell biological pathways that contribute to nerve repair after injury or neurodegeneration.

Objective B-cell activating factor (BAFF) is essential for B-cell survival and innate immune activation, and its ...

Immune cell therapies have transformed the treatment of certain blood cancers over the past decade. However, when it comes to ...

Hexarelin is a synthetic hexapeptide that emerged from late-20th-century efforts to design growth hormone–releasing peptides ...