Gene therapy with voretigene neparvovec-rzyl partially restores geniculostriate pathway function in LCA2 patients, improving visual processing. Initial LCA2 pathology shifts visual processing from the ...

Brain-stimulating contact lenses are as effective as Prozac at treating depression in mice via retinal pathways.

Vision is one of the most complex functions of our brain and requires a seamless interaction between many different brain structures to decode shapes, colours, depths, and movements and turn them into ...

Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different ...

Across the entire animal kingdom, visual images are processed by two major neuronal pathways that extract light and dark stimuli from visual scenes – ON (light on) and OFF (light off) pathways. Light ...

The 1950s were a relatively rudimentary era for experimental neurophysiology. Recording the electrical activity of neurons wasn’t uncommon, but the methods often demanded considerable patience and ...

Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply of nutrients and oxygen in the densely packed tissues is limited, leading to ...

Photoreceptors are specialized neurons that convert light into electrical signals that are processed in the visual cortex to form images. The RPE is a cell layer that is adjacent to the photoreceptors ...