As people age, muscles naturally lose mass and strength, a condition known as sarcopenia. The decline can make everyday activities harder and increases the risk of falls, disability and early death.

This genetic model suggests otherwise, indicating that coupled gating or other mechanical interactions, rather than CICR, drive activation of uncoupled RyR1 channels. Interestingly, the researchers ...

Following the US Food and Drug Administration (FDA) announcement on the phasing out of animal testing, the drug development industry has welcomed a wave of new approach methodologies (NAMs). However, ...

Muscles age differently than you think. Discover the science behind the aging muscle paradox—and how exercise can help you ...