In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...

A new artificial intelligence model can improve the process of drug and vaccine discovery by predicting how efficiently specific mRNA sequences will produce proteins, both generally and in various ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

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Silencing mRNA expression in dendritic cells did not impair T‑cell priming, including for SARS‑CoV‑2 antigens, suggesting that cross‑presentation by other cell types is sufficient to initiate immunity ...

The same groundbreaking technology that enabled rapid COVID-19 vaccine development is now poised to revolutionize medicine in ways that seemed impossible just a few years ago. Messenger RNA vaccines ...

A pizza shop with 30 delivery people ought to be able to deliver a lot of pizzas—if their cars don't break down on the way. Likewise, genes that produce a lot of messenger RNA (mRNA) molecules can ...

Researchers decoded how mRNA is transported in Ustilago maydis cells. They identified how binding motifs ensure accurate ...

Few medical advances in recent memory have sparked as much controversy as COVID-19 vaccines utilizing mRNA (messenger RNA). Currently, there are two such vaccines, from Pfizer-BioNTech and Moderna.