New simulator and computational tools generate realistic ‘virtual tissues’ and map cell-to-cell ‘conversations’ from spatial transcriptomics data, potentially accelerating AI-driven discoveries in ...
Modeling ligand–receptor signaling with NCEM. (a) UMAP of cells in MERFISH—fetal liver data. (b) Imputation of MERFISH data with scRNA-seq increases the number of genes that can be modeled with NCEMs, ...
Cell-to-cell communication is essential throughout all forms and stages of life, and many communication mechanisms are well studied. However, over the past few years, scientists have found increasing ...